intestinal obstruction in acute inhalational toluene 2,4-diisocyanate gas toxicity

نویسندگان

s shadnia toxicological research center, clinical toxicology department, loghman hakim hospital poison center, faculty of medicine, shahid beheshti university of medical sciences, tehran, iran

m ahmadimanesh pharmacology department, school of medicine, tehran university of medical sciences, tehran, iran

m ghazi-khansari pharmacology department, school of medicine, tehran university of medical sciences, tehran, iran

n zamani toxicological research center, clinical toxicology department, loghman hakim hospital poison center, faculty of medicine, shahid beheshti university of medical sciences, tehran, iran

چکیده

the isocyanates are widely used as precursors of polyurethane products, as well as carbamate insecticides. toluene 2,4-diisocyanate (tdi) is one of the most important commercially used isocyanates. humans may be exposed to tdi by inhalation, ingestion, dermal and eye contact. tdi is a powerful irritant to the mucosal membranes of the gastrointestinal and respiratory tracts, eyes and the skin. pulmonary manifestations, especially occupational asthma, are the predominant manifestations after tdi toxicity. herein, we present intestinal obstruction as an extraordinary manifestation of acute tdi toxicity after occupational exposure. tdi toxicity may cause intestinal obstruction.

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عنوان ژورنال:
international journal of occupational and environment medicine

جلد ۴، شماره ۳ July، صفحات ۲۶۴-۱۶۴

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